Spice is a chemically produced drug made to look like marijuana. Synthetic cannabinoids are sprayed on plant material to mimic marijuana. However, spice drugs actually have a different chemical makeup that acts differently in the brain. Specifically, they activate the CB1 receptor in the brain to a greater degree than does the THC in marijuana. Therefore, they have mind-altering effects that are typically much stronger than those produced by marijuana. Thus, spice abuse can have intense and dangerous symptoms.

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